If a bet within your combo bet is cancelled, the odds for your combo bet are automatically recalculated to remove that match from your selection.
If your remaining picks all result in wins, you'd receive winnings based on the recalculated odds excluding the cancelled match.
If one of your remaining picks results in a loss, your combo bet would result in a loss.
If you had a combo with 2 selections and 1 was cancelled, and the single bet went onto win, you'd receive 25xp (for every 1 coin bet) rather than 50xp.